Differentially expressed transcripts of Tetracapsuloides bryosalmonae (Cnidaria) between carrier and dead-end hosts involved in key biological processes: novel insights from a coupled approach of FACS and RNA sequencing

Shivam, Saloni; Ertl, Reinhard; Sexl, Veronika; El-Matbouli, Mansour; Kumar, Gokhlesh

doi:10.1186/s13567-023-01185-7

Veterinary Research

Table 2 Some major physiological functions of parasites and associated differentially expressed genes found in this study

From: Differentially expressed transcripts of Tetracapsuloides bryosalmonae (Cnidaria) between carrier and dead-end hosts involved in key biological processes: novel insights from a coupled approach of FACS and RNA sequencing

Function	Gene	Log₂ fold change (p value < 0.001) T. bryosalmonae (brown trout vs. rainbow trout)
Adherens junctions linking proteins	Catenin beta-like	−3.879
Actin polymerization	ras-like GTP-binding protein Rho1 isoform X2	−3.985
	ras-related GTP-binding protein A	2.796
	ras-related protein Rac1	−14.379
	T-cell activation Rho GTPase-activating protein	−1.711
	rho GTPase-activating protein 5 isoform X1	1.361
	rho GTPase-activating protein 39-like	1.948
	rho-associated protein kinase 1 isoform X1	1.980
	Afadin isoform X5	5.159
Adhesion molecules	Putative alpha P integrin isoform X1	−3.688
Adhesion molecules	Neural cell adhesion molecule 2	5.028
Tight junction proteins	Tetraspanin-9	1.769
Tight junction proteins	Tetraspanin-4	2.245
Extracellular matrix	fibronectin type-III domain-containing protein 3 A isoform X1	1.295
	collagen alpha-1 (XII) chain	3.639
	matrix metalloproteinase-25-like	3.271
Integrin-cytoskeleton links	talin-1 isoform X1	1.55
	alpha-actinin-1 isoform X3	2.113
	alpha-actinin, sarcomeric-like isoform X2	−5.290
	AChain A, X-ray structure of the human alpha-actinin isoform 3	−3.039
Nucleotide transporter	adenosine 3’-phospho 5’-phosphosulfate transporter 1	4.3565
Amino acid transporters	ATP-binding cassette sub-family G member 4-like	1.801
	ATP-binding cassette sub-family A member 12	1.537
	high affinity cationic amino acid transporter 1-like	3.088
	cationic amino acid transporter 2-like	3.310
Ion transporters (channel/Pore type transporters)	solute carrier organic anion transporter family member 4A1 isoform X2	−1.594
	vesicular glutamate transporter 2-like	2.149
	voltage-dependent calcium channel type A subunit alpha-1-like	4.013
	voltage-dependent N-type calcium channel subunit alpha-1B-like isoform X1	5.495
Ion transporters (ATP driven Na + dependent or cotransporters	Kanadaptin	1.478
	putative glycerol-3-phosphate transporter 5	1.407
Cell signalling	EGF-like domain-containing protein	6.451
Cell signalling	CREB-binding protein	−5.874

The table describes some of the key physiological functions of differentially expressed transcripts identified in this study. The log₂ fold change of the parasite transcripts between brown trout and rainbow trout at a p value < 0.001 are presented.

Back to article page

ISSN: 1297-9716

Contact us

Submission enquiries: veterinary.research@inrae.fr
General enquiries: info@biomedcentral.com