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Figure 8 | Veterinary Research

Figure 8

From: Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro

Figure 8

Schematic model of the mechanism underlying DHM-mediated inhibition of on ASFV replication. ASFV infection induces the expression of pro-inflammatory cytokines by activating the TLR4/MyD88/MAPK/NF-κB signaling pathway. Concomitantly, ASFV infection activates the ROS-NLRP3 inflammasome signaling cascade to induce pyroptosis. However, DHM treatment downregulates these signaling cascades and inhibits ASFV replication.

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Veterinary Research

ISSN: 1297-9716