A prospective CSFV-PCV2 bivalent vaccine effectively protects against classical swine fever virus and porcine circovirus type 2 dual challenge and prevents horizontal transmission

Table 3 Groups of conventional pigs and vaccination-challenge schedules

Groups^a	Vaccines^a	Immunization schedules	Challenge^b
D (n = 5)	CSFV-PCV2 bivalent vaccine	One dose at 4 weeks of age	PCV2
E (n = 5)	Placebo	One dose at 4 weeks of age	PCV2

^aFour-week-old conventional pigs were randomly divided into two groups and intramuscularly immunized with one dose (2 mL/dose) of CSFV-PC2 bivalent vaccine or placebo.
^bPigs in Groups D and E were challenged intramuscularly with 1 × 10⁵ TCID₅₀ of PCV2 (CYC08 strain) at 8 weeks of age.

ISSN: 1297-9716