Figure 7

The effect of MKP1 on CP-II cell proliferation and apoptosis. CP-II cells were transfected with pcDNA3.1-MKP1 (over MKP1), empty vector (pcDNA3.1), Si-MKP1 or Si-NC for 24 h and then infected with 200 µL of MG-HS. Overexpression of MKP1 was denoted as Over-MKP1; the negative control for MKP1 overexpression was denoted as pcDNA3.1; the MKP1 inhibitor was denoted as Si-MKP1; and the negative control for MKP1 inhibitor was denoted as Si-NC. A CCK-8 kit was used to detect cell proliferation at different times (A, B). After 48 h of treatment, the apoptotic cell ratio was analysed by flow cytometry. (C). A CCK-8 kit was used to detect cell proliferation at different times. All data from the experiments carried out independently three times are shown as the mean value ± SD, and * p < 0.05, ** p < 0.01 indicated significant differences.