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Figure 2 | Veterinary Research

Figure 2

From: Low let-7d microRNA levels in chick embryos enhance innate immunity against Mycoplasma gallisepticum by suppressing the mitogen-activated protein kinase pathway

Figure 2

Let-7d is involved in the regulation of MAPK by targeting MKP1. A KEGG pathway analysis of let-7d target genes. B GO term analysis of let-7d target genes. C Conservation of the let-7d target sequence in the MKP1 3’-UTR among different species and conservation of the let-7d sequence among different species. D The relative level of MKP1 in chicken embryonic lungs. E The mRNA and protein levels of MKP1 in CP-II cells. F The dual-luciferase reporter assay was performed in CP-II cells. The ratio of Renilla activity: Firefly activity represents luciferase activity. The data are presented as the means ± SDs (n = 4). Different lowercase letters represent p < 0.05. *p < 0.05, **p < 0.01.

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Veterinary Research

ISSN: 1297-9716