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Table 1 Differential abundance analysis of the antibiotic resistance genes in the porcine fecal samples

From: Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur

 

ARG

baseMean

Log2Foldchange

q-value

Mechanism

Ceftiofur

tetQ

6.27

2.14

0.05

Tetracycline resistance ribosomal protection proteins

Cefquinome

mel

8.51

2.58

0.00

MLS resistance MFS efflux pumps

tetQ

8.33

2.54

0.00

Tetracycline resistance ribosomal protection proteins

ErmF

7.81

2.43

0.00

23S rRNA methyltransferases

CfxA6

4.21

2.16

0.03

Class A beta-lactamases

lsaB

7.71

1.76

0.02

Multi-drug ABC efflux pumps

tet(40)

7.37

1.68

0.03

Tetracycline resistance ribosomal protection proteins

  1. Comparison of samples collected immediately after treatment (ET) with either ceftiofur (3 mg.kg−1 intramuscular, 3 consecutive days) or cefquinome (2 mg.kg−1 intramuscular, 5 consecutive days) to those collected from the control group at the same timepoint.
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Veterinary Research

ISSN: 1297-9716