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Figure 5 | Veterinary Research

Figure 5

From: NDV-induced autophagy enhances inflammation through NLRP3/Caspase-1 inflammasomes and the p38/MAPK pathway

Figure 5

NDV infection triggers mitochondrial damage and mitophagy in DF-1 cells. A TEM findings. (panel a) DF-1 cells were mock-treated as a negative control. Cells were infected with NDV at an MOI of 1 for (panels b and c) 9 h, (panel d) 12 h, and (panels e and f) 15 h. Bars, 1 μm (panels a–f). B Confocal fluorescence microscopy. DF-1 cells transfected with Dsred-Mito-EGFP were either NDV-infected or mock-treated (negative control). Mitochondrial fluorescence was evaluated 24 h post-infection. NDV: Newcastle disease virus.

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