Figure 5
The localization and quantification of CD172a + cells in the lamina propria treated with RSG. The distribution (A) and the number of CD172a+ cells in the lamina propria of mock-inoculated (B) or EHV-1 neurological strain 03P37 inoculated (C) nasal mucosa explants at 72 hpi and treated with RSG 12 h prior to or at the same time of the mock or viral inoculation at a concentration of 10 μM or 30 μM. ROIWI is the region of interest including the epithelium and the lamina propria with EHV-1 infection in the epithelium whereas ROIWOI is the region of interest without EHV-1 infection in the epithelium (two-way ANOVA; *P < 0.05; **P < 0.01). EHV-1 infected cells (red); CD172a+ cells (green). The white line drawn on the image represents the BM. Scale bar: 50 µm.