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Figure 4 | Veterinary Research

Figure 4

From: CCL2 and CCL5 driven attraction of CD172a+ monocytic cells during an equine herpesvirus type 1 (EHV-1) infection in equine nasal mucosa and the impact of two migration inhibitors, rosiglitazone (RSG) and quinacrine (QC)

Figure 4

Viral production and plaque formation of EHV-1 in equine nasal mucosa. Viral production (A) at 0, 2, 24, 48 and 72 hpi and plaque formation (B) at 72 hpi in nasal mucosa explants inoculated with EHV-1 neurological strain 03P37 and treated at the same time with RSG or QC at different concentrations (1 μM, 3 μM, 10 μM, 30 μM). The number of individual EHV-1 infected cell in the lamina propria of nasal mucosa explants (C) treated with RSG or QC 12 h prior to or at the same time of EHV-1 inoculation. ROIWI is the region of interest including the epithelium and the lamina propria with EHV-1 infection in the epithelium whereas ROIWOI is the region of interest without EHV-1 infection in the epithelium (two-way ANOVA; **P < 0.01; ***P < 0.001)

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Veterinary Research

ISSN: 1297-9716