Virus | Replication in guinea pigs | Contact transmission in guinea pigs | |||||||
---|---|---|---|---|---|---|---|---|---|
Virus titers determined on day 3 post inoculation in | Seroconversion: positive/total | Seroconversion: positive/total (HI titers) | |||||||
Nasal wash (log10EID50 ± SD /mL) | Organ (log10EID50 ± SD /g) | ||||||||
Lung | Trachea | Spleen | Kidney | Brain | Inoculated | Contact | |||
HD-160A | 4.5 ± 1.2 | 2.5 ± 0.2 | 0.8 ± 0.1 | –a | – | – | 2/2 | 3/3(40,80,40) | 2/3(0,20,20) |
HD/05 | – | 1.2 ± 0.2 | – | – | – | – | 0/2 | 0/3 | 0/3 |