Table 1 General litter information and the clinical signs of piglets and sows after PEDV inoculation (before challenge)

A

7; 0; 1

3; NA

Iowa106 (P0); 12; F&T 2×, filtrated

100 (6/6)

0 (0/5)

11.24 ± 1.80^a,b

1

1.80 ± 0.45^b

4.20 ± 0.84^c

7.00 ± 0.71^a,b

NA

NA

0

0

9.46

B

14; 3; 1

3; 1.67 ± 0.31^b

Iowa106 (P1); 10; F&T 1×,

100 (10/10)

75 (6/8)

11.08 ± 0.05^b

2

4.67 ± 0.58^a

6.33 ± 0.57^a,b

8.33 ± 1.53^a

6.75 ± 1.71^a

−0.28 ± 0.16^c

4

4

11.08

C

12; 1; 1

4; 1.8 ± 0.10^b

Iowa106 (P1); 12; F&T 2×

100 (10/10)

0 (0/10)

12.67 ± 0.48^a

2

4.00 ± 1.11^a

5.78 ± 0.97^b

6.56 ± 0.73^b

1.11 ± 0.93^c

−0.1 ± 0.20^c

1

2

11.60

D

11; 0; 1

4; 2.2 ± 0.30^a

Iowa106 (P1); 12; F&T 2×

100 (10/10)

0 (0/10)

12.17 ± 0.47^a

2–3

1.56 ± 0.73^b

3.44 ± 1.01^c

6.00 ± 1.41^b

0.00 ± 0.00^d

0.5 ± 0.30^b

0

0

9.40

E

13; 2; 0

4; 1.60 ± 0.42^b

PC21A (P2); 10; F&T 1×

100 (11/11)

55 (6/11)

11.80 ± 0.89^a

1

5.25 ± 0.96^a

7.20 ± 0.45 ^a

8.25 ± 1.26^a

3.22 ± 2.17^b

0.03 ± 0.31^c

2

5

9.67

F

10; 2; 1

4; 1.80 ± 0.16^b

Mock

0 (0/7)

0 (0/7)

ND

ND

0.00 ± 0.00^c

0.00 ± 0.00^d

0.00 ± 0.00^c

0.00 ± 0.00^d

0.95 ± 0.16^a

0

0

ND