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Figure 1 | Veterinary Research

Figure 1

From: Identification of systemic immune response markers through metabolomic profiling of plasma from calves given an intra-nasally delivered respiratory vaccine

Figure 1

Sampling points for metabolomic profiling of plasma in calves following vaccination and subsequent BPI3V challenge. Male Holstein Friesian calves were dosed with Pfizer Rispoval®PI3 + RSV intranasal vaccine (vaccinated) or empty PLGA nanoparticles (non-vaccinated) at day 0. A secondary booster dosage was administered at day 35. At day 70 all animals were experimentally challenged with BPI3V via nasal inoculation. At day 6 during the BPI3V challenge study 3 calves per group were sacrificed for viral isolation and histology. Sampling points for metabolomic profiling of plasma are indicated throughout.

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Veterinary Research

ISSN: 1297-9716