Functional investigation of a QTL affecting resistance to Haemonchus contortus in sheep

Table 2 List of the genes considered for gene expression analysis

		Gene name	OAR	Position	Related GO functions	Tissue in which the gene was tested
Within QTL		PAPP-A2	12	55 757 260	Regulation of Insulin-like Growth Factor (IGF) activity	AFM, ALN
	Innate response	LGALS15	-	-	Carbohydrate binding	AFM
		ITLN2	1	110 480 137	Response to nematode	AFM
		TFF3	1	260 633 891	Molecular function	AFM
		IL4	5	19 237 699	Cytokine activity	AFM, ALN
		IL5	5	19 436 357	Cytokine activity	AFM, ALN
		IL13	5	19 261 902	Cytokine activity	AFM, ALN
Outside QTL	Acquired response	TNFα	20	26 854 381	Cytokine activity	AFM, ALN
		IFNγ	3	151 528 005	Cytokine activity	AFM, ALN
		TNFRSF4	12	49 359 903	Tumor necrosis factor-activated receptor activity	ALN
		CCL26	24	33 952 859	Chemokine (C-C motif) ligand 26	ALN
		CXCL14	5	44 432 648	Chemokine (C-X-C motif) ligand 14	ALN

The genes whose expression level has been measured are listed with their respective gene name, chromosome (OAR) and starting position (given in bp) and gene ontology function as provided by the NCBI’s website [31]. Expression levels were measured in the abomasal fundic mucosa (AFM)or in the abomasal lymph node (ALN) or both.

ISSN: 1297-9716