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Table 2 Effect of Rabbit Hemorrhagic Disease virus (RHDV) infection on mRNA levels of genes related to autophagy

From: Autophagic response in the Rabbit Hemorrhagic Disease, an animal model of virally-induced fulminant hepatic failure

 

Control

12 h

18 h

24 h

30 h

36 h

Beclin-1

100 ± 11

118 ± 8

203 ± 16*

253 ± 36*

105 ± 6

87 ± 7

UVRAG

100 ± 6

104 ± 8

227 ± 19*

131 ± 15

81 ± 9*

99 ± 5

Atg5

100 ± 5

125 ± 11*

163 ± 19*

139 ± 7*

87 ± 7

63 ± 5

Atg12

100 ± 9

173 ± 12*

296 ± 41*

177 ± 9*

104 ± 8

82 ± 7

Atg16L1

100 ± 10

106 ± 9

223 ± 6*

140 ± 12*

130 ± 7*

106 ± 10

p62/SQSTM1

100 ± 4

145 ± 6*

192 ± 8*

202 ± 8*

86 ± 6

69 ± 4*

BiP

100 ± 7

118 ± 17

177 ± 41*

304 ± 29*

241 ± 39*

184 ± 18*

CHOP

100 ± 8

169 ± 10*

211 ± 19*

540 ± 79*

158 ± 9*

161 ± 13*

GRP94

100 ± 4

80 ± 4*

163 ± 5*

412 ± 54*

314 ± 13*

226 ± 21*

  1. Levels of mRNA were analyzed by real-time PCR assays. Data, normalized against β-Actin, are presented as percentage change from the control group. Values are expressed as means±S.E.M (n = 6). *P<0.05, compared with Control.