Figure 1

Resistance and susceptibility to Johne’s disease in a red deer stud herd. (A) Diagnosis of MAP infection by Paralisa™ in animals of distinct pure breeds (anonymised to A – G, n = 1135 animals total). Differences in reactivity rate are statistically significant (p < 0.01) between breeds with the exception of differences between Breeds A, C and G. (B) Deaths from clinical Johne’s disease in the different pure breeds (A – G) recorded over a 6 year period prior to serological testing (n = 1244 animals total). Differences in death rate are statistically significant (p < 0.01) between breeds A – C and breeds E – G. A high level of exposure of all animals confirms that the resistant breeds, with low incidence of MAP infection and no deaths from Johne’s disease (breeds A – C), have a resistant phenotype and do not include unexposed indeterminate animals.