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Table 2 Cytokine gene expression expressed as mean ± SEM of the mRNA molecules/pg of total RNA in the liver and hepatic lymph nodes (HLN) of uninfected control (UC), infected control (IC), vaccine 1 (V1) and vaccine 2 (V2)

From: Evaluation of Th1/Th2, regulatory cytokines and transcriptional factor FoxP3 in sheep immunized with a partially protective and non-protective vaccine and challenged with Fasciola hepatica

 

Liver

Group

IL-4

IFN-ɣ

TGF-β

IL-10

FoxP3

IFN-ɣ/IL-4

UC

0.02 ± 0.01

0.03 ± 0.01

2.83 ± 0.61

0.07 ± 0.01

0.02 ± 0.01

1.85 ± 1.47

IC

0.06 ± 0.03

0.04 ± 0.01

6.28 ± 1.38

0.09 ± 0.03

0.07 ± 0.04

0.80 ± 0.41

V1

0.04 ± 0.02

0.04 ± 0.02

7.05 ± 1.92

0.09 ± 0.04

0.06 ± 0.02

1.21 ± 1.10

V2

0.11 ± 0.12

0.05 ± 0.02

7.16 ± 2.11

0.13 ± 0.07

0.08 ± 0.06

0.90 ± 0.46

 

HLN

UC

0.44 ± 0.12

0.38 ± 0.15

33.09 ± 2.18

0.63 ± 0.32

1.09 ± 0.17

0.95 ± 0.56

IC

0.61 ± 0.12

0.26 ± 0.15

33.68 ± 9.10

0.63 ± 0.13

1.23 ± 0.55

0.42 ± 0.19

V1

0.47 ± 0.18

0.16 ± 0.08

32.20 ± 3.44

0.55 ± 0.08

0.86 ± 0.20

0.35 ± 0.42

V2

0.55 ± 0.13

0.16 ± 0.03

37.18 ± 8.27

0.49 ± 0.14

1.28 ± 0.29

0.31 ± 0.11