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Table 2 Relative expression of immune related genes in different tissues of Atlantic salmon after SAV-3 infection

From: Gene expression studies of host response to Salmonid alphavirus subtype 3 experimental infections in Atlantic salmon

Tissues

Spleen

Head kidney

Pancreas

Heart

Genes

Weeks

 

2

4

8

2

4

8

2

4

8

2

4

8

IFN-γ

0.7 ± 0.2

2.4 ± 0.5*

0.8 ± 0.1

3.0 ± 0.7*

4.1 ± 1.1*

0.8 ± 0.1

3.4 ± 0.7

7.2 ± 0.9*

1.5 ± 0.4

1.1 ± 0.2

6.3 ± 3.0*

89.3 ± 23.2*

TNF-α

0.5 ± 0.1

0.7 ± 0.1

1.4 ± 0.4

1.2 ± 0.3

1.0 ± 0.3

0.6 ± 0.2

1.3 ± 0.3

1.4 ± 0.2

1.2 ± 0.1

2.2 ± 0.9

2.5 ± 0.3*

8.1 ± 1.5*

IL-12

0.7 ± 0.1

1.6 ± 0.2

0.8 ± 0.2

0.8 ± 0.1

1.0 ± 0.1

1.0 ± 0.1

2.2 ± 0.3

0.6 ± 0.1**

1.7 ± 0.4

1.0 ± 0.3

0.9 ± 0.2

3.3 ± 0.7*

IL-10

0.9 ± 0.1

7.5 ± 1.4*

2.8 ± 0.5*

10.0 ± 1.6*

21.2 ± 4.1*

4.7 ± 1.1*

3.1 ± 0.6

23.9 ± 6.5*

3.2 ± 0.8*

1.1 ± 0.3

4.1 ± 1.5

37.3 ± 7.6*

IL-8

1.5 ± 0.3

1.5 ± 0.6

3.0 ± 0.6*

1.0 ± 0.4

2.3 ± 0.8

1.9 ± 0.5

1.3 ± 0.2

1.7 ± 0.2

1.4 ± 0.2

1.0 ± 0.1

1.7 ± 0.3

5.7 ± 1.2*

CD3-ε

0.9 ± 0.1

0.9 ± 0.1

0.7 ± 0.1

0.6 ± 0.1

1.6 ± 0.2

1.7 ± 0.4

1.5 ± 0.3

1.4 ± 0.1

1.7 ± 0.2*

1.0 ± 0.2

1.3 ± 0.2

10.4 ± 1.9*

CD4

0.7 ± 0.1

1.3 ± 0.1

1.1 ± 0.2

0.7 ± 0.1

0.9 ± 0.1

1.1 ± 0.1

1.2 ± 0.2

1.1 ± 0.2

1.9 ± 0.3*

1.1 ± 0.5

2.5 ± 0.7

11.1 ± 1.8*

CD8

1.2 ± 0.2

1.3 ± 0.3

1.2 ± 0.3

1.0 ± 0.3

0.5 ± 0.1**

0.7 ± 0.1

0.4 ± 0.0**

0.7 ± 0.1

2.1 ± 0.2*

1.0 ± 0.2

0.8 ± 0.3

51.6 ± 9.7*

TCR-α

1.5 ± 0.2

1.0 ± 0.1

1.0 ± 0.2

0.8 ± 0.2

0.6 ± 0.1**

0.7 ± 0.1

1.4 ± 0.1

1.4 ± 0.2

2.0 ± 0.3*

0.5 ± 0.1

0.8 ± 0.2

16.4 ± 2.5*

MHC I

1.7 ± 0.2

3.1 ± 0.2*

1.5 ± 0.2

1.7 ± 0.2*

2.4 ± 0.2*

1.5 ± 0.1*

3.7 ± 0.7*

1.4 ± 0.2

2.1 ± 0.2*

1.5 ± 0.3

4.4 ± 0.5*

8.2 ± 0.8*

MHC II

1.1 ± 0.1

1.6 ± 0.2

1.2 ± 0.2

0.9 ± 0.1

1.7 ± 0.2*

1.4 ± 0.2

1.8 ± 0.3

1.4 ± 0.2

1.6 ± 0.3

0.5 ± 0.1**

1.5 ± 0.3

5.1 ± 0.8*

  1. The results are shown as mean fold change ± standard error of virus infected group relative to the mean of the control group. Key: *Significantly up-regulated; **Significantly down regulated, otherwise not differentially induced (P > 0.05).